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From first being prescribed for diabetes management to now being used for weight loss, GLP-1s have caused health care providers and insurers to examine the long-term effects of the drug and the costs associated with their use

Implications for pharma companies: Pharmas entry into the trillion-dollar club is largely driven by success in a treatment category (obesity) poised to reshape consumer health and wellness, given the massive demand for better weight loss solutions

Chinese fried dishes, cream sauces, and excess oil can trigger mild stomach upset in susceptible patients, though this typically resolves as your body adjusts

Where semaglutide targets one receptor and tirzepatide targets two, retatrutide targets three and the clinical trial results reflect exactly that step change in biological leverage

Cost: $543.51-$815.27 without insurance

Ozempic is a GLP-1 receptor agonist, while Mounjaro is a dual GLP-1/GIP agonist