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A large review of gut-directed hypnosis, typically administered in 6 to 12 weekly sessions, found it was a highly effective and adaptable treatment option in refractory FGIDs, but is limited by time requirements, cost, general availability, and lower effectiveness when delivered outside specialized research centers [129,130]

Clinicians evaluate potential interactions, cumulative side effects, and overall adherence

Physiol Rev (2017) 97(1):41163

Individual tolerability varies based on genetic factors, baseline health status, and personal sensitivity to GLP-1/GIP signaling

GLP-1 receptor activation reduces appetite and delays stomach emptying, cutting energy intake

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