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Clinical data shows this mechanism is one reason GLP-1 medications are so effective at reducing overall calorie intake without conscious restriction

Furthermore, some evidence suggests improved menstrual frequency and ovulatory function

This results in calcium-induced release of insulin granules (23)

With careful monitoring, guidance, and ongoing support, patients receive a structured plan designed to improve overall wellness while working toward long-term weight goals

It highlights that GLP-1 is no longer viewed just as a "gut hormone" but as a systemic regulator of immune and inflammatory responses

NICE guidance emphasises individualised care, and treatment decisions should be made collaboratively between patients and healthcare professionals, considering the overall benefit-risk profile for each individual