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This means ketone levels can rise even when blood glucose looks normal because reduced food intake and lower insulin doses can shift the body toward fat burning

The T2D trial showed a similar safety profile, with SAEs occurring in 48% of participants at the retatrutide groups vs

How GLP-1 Medications Work GLP-1 medications work by mimicking the action of the natural hormone GLP-1, which is produced in the small intestine

PubMed, Maselli, Daniel, et al

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Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): A randomised, open-label, parallel-group, multicentre, phase 3 trial