glp 1 drugs and blood clots Wegovy Lawsuit [2026 Update] Does GLP-1 Cause Blood Clots?

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In respect to their cardiovascular effects among patients with T2DM, both GLP-1RAs and SGLT2is have been shown to reduce the risk of MACE (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke), with GLP-1RAs reducing the risk of non-fatal stroke to a greater extent [3, 6]

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Therefore, DPP-4 inhibitors are a safe choice for the elderly and those with kidney disease, as they help control diabetes without the risk of causing further harm [7]

In light of this potential significant safety issue, the development of Lotiglipron has been discontinued, meaning the drug did not progress to further clinical trial stages to evaluate its efficacy and safety