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The FDA has been relatively progressive in approving GLP-1 products for expanded indications, including cardiovascular risk reduction

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The Peptide Problem: Why Oral GLP-1 Was So Difficult Glucagon-like peptide-1 is a 30-amino-acid incretin hormone secreted by enteroendocrine L-cells in the distal small intestine in response to nutrient ingestion

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doi:10.1056/NEJMoa0905561 Patel MR, Mahaffey KW, Garg J, et al

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