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Much of the focus on the impact of GLP-1 receptor agonists (and combination drugs with components that target other receptors such as gastric inhibitory polypeptide collectively termed GLP-1s in this article) to date has been on their potential to improve long-term health outcomes for people with type 2 diabetes, obesity, and related cardiovascular diseases

Others may require carefully titrated adjustments over time

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Weight and Hormones One of the most significant ways Mounjaro may influence the menstrual cycle is through weight loss, which has a profound effect on hormonal balance

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What has changed is the size of the audience that needs it and the urgency of the timeline