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The exenatide group in this study, however, showed a significant increase in the mean cardiac output by 1.2 L/min, a reduced total peripheral resistance by the mean of 120 dyns/cm 5 , and a significantly reduced urinary sodium: creatinine ratio without a significant change in the BP [39]

Until approval, retatrutide is unavailable for general use, and any compounded versions see heavy regulatory oversight

This difference reflects semaglutide's direct appetite-suppressing action on the central nervous system

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doi: 10.1002/brb3.1505 238 PanagakiTGenglerSHolscherC
