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Clinical trials designed to take into account the inherent redox state of the patients involved (the lower the redox state, the less effective antioxidants will be), the stage of AD or mild cognitive impairment (MCI) involved, and specifically targeted antioxidants conceivably may permit a closer examination of the potential of antioxidant therapy to slow or perhaps retard the rate of cognitive decline in these disorders

[Google Scholar] 54.Liu EY, Wu J, Cao WD, Zhang JN, Liu WP, Jiang XF, and Zhang XA

P.CuenoudB.XinL.et al (2025)

doi: 10.1007/s00299-021-02667-8 49 KangF

Homocysteine like other biological thiols, may play an important role in protection of cells against reactive oxygen species and some reactive intermediate products

Although the task is challenging, success is possible