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Description
It has been reported that tranilast improves the prognosis of ischemic stroke patients by stimulating M2 polarization of microglia, improving sensorimotor function and inhibiting the production of inflammatory cytokines, thereby reducing infarct size in stroke model mice [188]

Toxicology Reports

[DOI] [PubMed] [Google Scholar] 76.Zhang N.N., Park D.K., Park H.J

For example, the fibronectin-binding integrin 3 heterodimer is associated with tumor cell survival during tumor development (Young et al., 2020)

Neurotoxicology 31:694700

This reduction was achieved by triggering the collapse of the DIPMA structure through the protonation of its tertiary amine structure in an acidic endosomal environment
