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Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage

On April 30, 2026, the FDA proposed formally excluding semaglutide and tirzepatide from the 503B bulk drug substances list, a move that would close the last major large-scale compounding pathway for these medications if finalized

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The article reviews the pathophysiology of both pediatric obesity and MASLD, explores current therapeutic strategies, and discusses the emerging role of glucagon-like peptide-1 receptor agonists, such as liraglutide, semaglutide, exenatide, and dulaglutide, in managing obesity, as well as explores current limited pediatric literature on the use of these medications in MASLD