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The estimated treatment differences (ETDs [95% CIs]) for oral semaglutide 3 mg, 7 mg and 14 mg vs placebo were 11 (13, 9) mmol/mol, 16 (18, 13) mmol/mol and 17 (19, 15) mmol/mol, respectively

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Results Four head-to-head randomized controlled studies with 1755 patients were included

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Doctors stress GLP-1s are most effective as part of a broader lifestyle change, and should not be used as a replacement for diet and exercise.