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As the disease progresses, A deposits, neurofibrillary tangles, damaged neurons, brain insulin resistance, and ER stress are thought to provide feedback stimuli for inflammation [151,152]

Some patients may question whether a faster titration is possible, particularly if they previously tolerated higher doses well

Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with Saxenda

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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Cena H., Chiovato L., Nappi R.E

Goldman, 2023