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Description
MDL 3163, created in December 2025 for claims that semaglutide-class drugs cause non-arteritic anterior ischemic optic neuropathy (NAION), held its gating "Science Day" on June 2, when Judge Karen S
10.1056/NEJMoa012908 146
These alterations play a role in chronic inflammation ("inflammaging"), reduced nutrient uptake, impaired immunity, and cognitive modification
This makes it relevant not only to obesity but also to MASH/NASH and broader metabolic syndrome

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Physiol Behav (2006) 89(4):4604
