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Description
Central administration of GLP-1RAs or SGLT-2is could increase the expression of c-Fos in neurons within the PVN, amygdala, NTS, AP, and ARC, 56 , 96 which was consistent with the expression of GLP-1R/SGLT-2 in the whole CNS
8 Additionally, a small number of animal and clinical trials have highlighted the benefits of individual GLP-1 RAs, including exenatide and lixisenatide

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For a closer look at those symptoms, see our managing nausea on semaglutide guide

Fact: Large human studies have not shown a clear or consistent increase in thyroid cancer risk

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