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Hathur, B

It also addresses current gaps in understanding and areas for further research

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This review explores tirzepatide's mechanisms of action, clinical efficacy, and safety profile, with particular attention to its impact on T2DM, obesity, cardiovascular health, metabolic-associated fatty liver disease (MAFLD), chronic kidney disease (CKD), and neurological disorders such as Alzheimer's and Parkinson's diseases

Although direct monitoring of fetal blood glucose concentrations immediately post-Sem injection was not performed, the absence of a reduction in the body weights of fetuses from glucose-supplemented dams discounts the notion that the decrease in fetal glucose levels is responsible for the fetal growth restriction induced by maternal GLP-1R activation

(US) Innovent Biologics (China) Shanghai Benemae Pharmaceutical (China) PegBio Co Ltd