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Unapproved peptides, such as Retatrutide, have not been assessed by the TGA for safety, quality or effectiveness

Some patients may experience dramatic improvements with relatively modest weight loss, while others require more substantial weight reduction to achieve similar benefits

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As of 2024, no such study currently exists for Mounjaro meaning we do not know if these same risk factors will be reduced

That means even modest weight loss can dramatically reduce joint load and discomfort