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For Black patients, 62% were from the South, 21% from the Northeast, 13% from the Midwest and 3% from the West

Semaglutide: Mechanism of Action and Clinical Value Mechanism of Action Semaglutide belongs to the class of GLP-1 receptor agonists (glucagon-like peptide-1), designed to mimic natural incretin hormones involved in glucose regulation and appetite control

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In trials for knee OA (TRIUMPH1 OA basket and TRIUMPH4), the primary endpoint includes the average change in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale score, and key secondary endpoints include change in the WOMAC physical function subscale score and the percentage of participants with a 50% reduction in the WOMAC pain subscale score

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