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However, for patients who clearly have a severe intoxication, naloxone administration should not delay more definitive and evidence-based therapies (e.g., intubation and hemodialysis)

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1C), the methyltransferase that was also significantly elevated in SSc skin biopsies 24

Zhao, J., Du, F., Shen, G., Zheng, F

Cutting-edge directions and future prospects of neuronal metabolism research Looking ahead, integrating multi-omics approaches such as 4-dimensional fast data-independent acquisition (4D-FastDIA) quantitative proteomics and targeted metabolomics [e.g., dissecting how Danggui-Shaoyao-San regulates the glycogen synthase kinase 3 beta (GSK3)/PGC1 signaling pathway to improve brain glucose uptake and mitochondrial complex function in AD models (Wu et al., 2024)] with computational modeling is unraveling systematic regulatory networks in neuronal energy metabolism, pinpointing critical nodes like pyruvate dehydrogenase complex phosphorylation and dynamic MCT2 transporter expression (Brown and Ransom, 2007)

& Committee on Research Priorities for Preventing and Treating Alzheimers Disease and Related Dementias