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reported in the early 90 s that GLP-1 interacted with exendin receptors on dispersed acini from guinea pig pancreas 22,23 , and these concerns were increased with the results from the LEADER trial showing a numerically greater, although statistically not significant, number of cases of pancreatic cancer in the liraglutide arm compared to the placebo 20

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Scorrano et al., 2019)

GLP-1 medications work by increasing insulin secretion, decreasing glucagon secretion, delaying gastric emptying, and reducing appetite, which collectively lead to weight loss and improved metabolic health

When substantial fat volume is lost particularly over a compressed timeframe the skin and underlying soft tissues do not always rebound

There are several ways supplements can help