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The anxiolytic-like, antidepressant-like, anticonvulsant, sedative effects and the anti-inflammation of neophytadiene (Bhardwaj et al., 2020

Experimental and clinical psychopharmacology
Significance of Artemisia Vulgaris L

These metabolites induced cell cycle arrest and apoptosis in lung carcinoma cells, linking gut microbiota alterations to anti-cancer activity against tobacco smoke-related carcinogenesis [124]

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So, stating that nicotine is toxic, in a certain sense, is very true, but so is water, as about 4 liters will kill a person