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It is designed to activate both GIP and GLP-1 receptors with specific binding affinities: GIP receptor affinity comparable to native GIP, and GLP-1 receptor affinity approximately 5-fold weaker than native GLP-1, resulting in an imbalanced agonist profile that favors GIP receptor activation

Persistent or worsening symptoms are not expected and should be discussed with a medical professional

Rybelsus is taken as an oral tablet and is not approved to reduce risk of cardiovascular disease in those with type 2 diabetes, as is Ozeympic

PubMed Bhasin S, et al

At 20 mg/mL, the same doses require 12.5 units and 50 units respectively

Ask your prescriber how these theoretical risks apply to your situation