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Pregnant and Breastfeeding Women: IV therapy should only be administered under medical supervision

10.1083/jcb.200611044

Additional experiments also need to be performed to eliminate the possibility of contraindications of any possible adjuvants with the ASMs

Also, serious adverse effects of long-term opioid therapy (eg, opioid use disorder [addiction], overdose, respiratory depression, death) are being increasingly recognized

They are also recommended to vegans, strict vegetarians, or anyone whose diet does not provide an adequate amount of naturally occurring or supplemented B12

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