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Ghrelin, the primary hunger hormone, typically rises during caloric restriction

The most common side effects are gastrointestinal, such as nausea, diarrhea, vomiting, and constipation

Review your current semaglutide dosage or tirzepatide dosage in units before your trip

Medical supervision helps confirm candidacy, guide dosing, monitor side effects, protect nutrition intake and adjust treatment when needed

Treatment begins at a low dose (2.5 mg weekly) and is gradually increased every four weeks (to 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg) as tolerated to minimize gastrointestinal side effects