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Taking it one day early means your previous dose is still at elevated levels when the new dose peaks, creating a temporary spike in GLP-1 receptor stimulation

doi: 10.1056/NEJMoa0808718
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[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Harrison SA, Bedossa P, Guy CD, et al

These side effects often improve over time

L., & Pepys, M
