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Ozempic was FDA-approved for type 2 diabetes in 2017, and Wegovy (a higher dose of semaglutide approved for weight loss) in 2021

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Studies such as the SUSTAIN and STEP trials have demonstrated their benefits in both glycemic control and weight reduction, positioning GLP-1 agonists as cornerstones in the treatment of metabolic disorders

For weight loss, schedule an online video consult with a provider through Success by Sesame, Sesame's weight loss program, to discuss your options and get an Rx if appropriate

Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine
