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Liu YW, Liu XL, Kong L, Zhang MY, Chen YJ, Zhu X, Hao YC

Inhibition of Cyclin Dependent Kinase 8(CDK8): A Novel Approach to Target the Leukemia Initiating Cells (LICs) in T-Cell Acute Lymphoblastic Leukaemia (T-ALL)
The anticancer activity of this compound is related to its pro-oxidant and antioxidant capacity due to its complex structure including double bond in the carbonic chain, the position and number of OH group and free phenolic hydroxyl in the catechol group, respectively ( via the active transport carried out by the carriers of monocarboxylic acid

Epigenetics: the origins and evolution of a fashionable topic

The general population may be exposed to low concentrations of N- nitrosopiperidine from cigarette smoke and certain foods (IARC 1978k)
Key Takeaway Glutathione and kojic acid are not competitors