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One significant concern is the increased risk of developing gallstones (cholelithiasis)

Type 2a SCAD demonstrates normal arterial segments proximal and distal to a dissection and does not extend into a distal vessel

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However, Retatrutide has not yet been approved by European and Dutch authorities and is therefore not yet available as a treatment

The most common side effects are gastrointestinal symptoms including nausea, vomiting, diarrhoea, and constipation, which are typically mild to moderate and improve with dose titration

By improving insulin sensitivity, Semaglutide helps reduce high insulin levels, which in turn can decrease androgen levels and alleviate some PCOS symptoms, including weight gain