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The detection signal is then generated in proportion to the amount of human subclass antibody

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Indeed, if we replace the models of two c-METs from our structure of c-MET/HGF holo-complex to the N-terminus disordered c-MET, the distance between the two IPT2 domains is increased from 20 to 44 , suggesting that the compact c-MET is not in an ideal conformation for activation, which supports our hypothesis

Also, the different mechanisms involved in the beneficial effects of MEM in the preclinical levels will be discussed

doi: 10.1007/s10552-009-9399-7