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NFB is a key transcription factor involved in inflammation, immune response, and cell survival

Explaining metabolic flexibility and how it can be improved [20:30]

Vedolizumab is a humanised monoclonal antibody that inhibits lymphocyte adhesion, particularly the mucosal addressin cell adhesion molecule-1 (MAdCAM-1), which is selective for 47 integrin[86]

By phagocytosing chemically modified low-density lipoprotein (LDL), these cells become foam cells, which make up the largest part of the core of the plaque

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Before a drug candidate can be tested in humans, it needs to pass through a rigorous preparation process that covers several interconnected areas