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Patients should work with their healthcare team to establish appropriate monitoring frequency and target ranges based on ADA recommendations

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In LepR-deficient Koletsky rats, the adenovirally induced expression of LepRs in ARC nucleus improves peripheral insulin sensitivity via enhanced suppression of hepatic glucose production, with no change in insulin-stimulated glucose uptake or disposal

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demonstrated that GLP-1 and its analog exendin-4 enhance the apoptosis of estrogen receptor-positive breast cancer cells in vitro (Ligumsky et al., 2012)

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