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[PubMed: 28845751] 458

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When oxidative stress is high, the ratio shifts toward GSSG as GSH is used up in antioxidant reactions

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Risk Factors That Increase Bone Resorption Low calcium and vitamin D intake Sedentary lifestyle Smoking and alcohol use Chronic stress and cortisol elevation High soft drink or caffeine consumption Protective Lifestyle Measures Weight-bearing exercise stimulates bone formation and reduces resorption

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