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What distinguishes the structure of glutathione is that Glu is linked to Cys in an amide linkage through carboxyl and not from carboxyl position

Staining was performed with an Alexa Fluor 488-conjugated goat anti-mouse secondary antibody (1:200, Invitrogen A-11001) and DAPI (Invitrogen, 1:5,000 dilution)

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Oxidative stress is frequently followed by CHK2 (Thr68) phosphorylation through ATM stimulation, signifying that ATM is a significant sensor of ROS in human cells [24]

However, IgG4 autoantibodies have been proven to be pathogenic in MuSK myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, acquired thrombotic thrombocytopenic purpura, and pemphigus [66]

J.Klein-FedyshinM.et al