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SP600125, a classical ATP-competitive inhibitor of JNK, has been reported to have protective effects against AIH in vivo and in vitro

While 7-HMR alone did not rescue dopaminergic cell loss in the acute toxin model (56), its ability to dampen neuroinflammation could be beneficial in a chronic setting or in combination with other therapies that promote neuron survival

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Several factors may contribute to this change

For significant or daily cravings, a physician consultation about FDA-approved medication options is recommended
