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lung, kidney, spleen, heart, liver, brain, muscle: n = 5

Hexamethonium itself reduced tyramine-induced norepinephrine overflow in SHR, possibly explained by inhibition of presynaptic, nicotinic receptors, which stimulated vesicular release ( From these experiments, it was concluded that 1 AR functioned as a presynaptic auto-receptor in peripheral sympathetic nerves and stimulated norepinephrine release

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