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Acid-related disorders Peptic ulcer disease (gastric & duodenal ulcers) Gastroesophageal reflux disease (GERD) / acid reflux ZollingerEllison syndrome (gastric acid overproduction) 2

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Other approaches for half-life extension PEGylation is another common strategy for enhancing in vivo stability of therapeutic peptides

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Immunotoxic destruction of distinct catecholamine subgroups produces selective impairment of glucoregulatory responses and neuronal activation