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When your fat cells become full for lack of a better term the fat ends up in your liver, your muscles, your pancreas, and it begins to cause metabolic havoc, he says

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The peptide's amino acid sequence remains the same, but its three-dimensional structure is irrevocably damaged, rendering it biologically inert

It's not a linear relationship, it's more of a curve
Hu W, Song R, Cheng R, Liu C, Guo R, Tang W, et al

doi: 10.1210/jc.2003-030738 [DOI] [PubMed] [Google Scholar] 38.Nasteska D, Harada N, Suzuki K, et al
