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The divergence of GLP1 neural circuitry between rats and mice are at least one likely culprit (Cork et al., 2015
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You can switch between metformin and Ozempic, says Pessah-Pollack

Patients in the conventional therapy group experienced significantly higher liver fat content vs

many people discontinue for legitimate reasons including cost, personal preference, or having reached a specific goal

If GLP-1 drugs prove effective in reducing cravings or reshaping reward response, they could become part of a broader toolkit for addressing: Alcohol use disorder Nicotine dependence Stimulant addiction Binge eating disorder Impulse control disorders However, experts emphasize that GLP-1 medications are not a stand-alone cure for addiction
