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Mitochondrial kappa class enzymes, contain a serine in the G-site and resemble theta class enzymes

Performed the experiments: MS SC JO AN OF

discovered that bvPLA2 may successfully suppress the development of Alzheimers disease in transgenic mice (Ye et al., 2016b)
CKD-MBD occurs in nearly every patient with stage 5 CKD (eGFR 14 grams) decreased the effectiveness of ACE inhibitor therapy and increased the risk for kidney failure

Specifically, the predicted distance and orientation probabilities were first converted into potentials, which are then used as restraints to be fed into Rosetta together with coarse-grained energy optimization
