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NDDSs offer several advantages, including an increased drug loading capacity, improved pharmacokinetic properties, passive or active targeting mechanisms for site-specific delivery, synergistic effects of multiple therapeutic agents, minimized drug resistance, and controlled release to enhance efficacy while reducing toxicity

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and the complex intratesticular autocrine-paracrine regulation

Finally, integration into existing wound-care protocols through collaborations with clinicians and industry partners can facilitate adoption

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