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Those with certain co-morbid conditions, or on certain drugs, seem more likely to be non-responders

Change in how much or how often you urinate, lower back or side pain, blood in your urine Unusual moods or behaviors, depression, thoughts of hurting yourself or others Blurred vision or any other change in vision Sudden and severe stomach pain, nausea, vomiting, fever, passing gas, stomach upset or bloating, yellow eyes or skin Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing Tell your doctor if you are breastfeeding, or if you have kidney disease, pancreas problems, diabetes, digestion problems, or a history of diabetic retinopathy or depression

This is particularly relevant for the long-acting weekly formulations, where minor variations in absorption rate would have minimal impact on overall therapeutic effect

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Karta Charakterystyki Produktu Leczniczego Trulicity 7