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Single intradiscal administration of the tumor necrosis factor-alpha inhibitor, etanercept, for patients with discogenic low back pain
Under physiological conditions, Nrf2 remains sequestered in the cytoplasm by its inhibitor, the Kelch-like ETC-associated protein 1 (Keap1), but oxidative or electrophilic stress triggers Nrf2 dissociation, nuclear translocation, and binding to antioxidant response elements (AREs), upregulating genes such as heme oxygenase-1 (HO-1), NAD(P)H quinone oxidoreductase 1 (NQO1), and glutathione S-transferases (GSTs) (Cuadrado et al., 2019)

Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma

Luo Q, Liang W, Zhang Z, Zhu Z, Chen Z, Hu J, et al
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doi: 10.1002/smll.202401369 84 ZallocchiM.VijayakumarS.FleegelJ.BatalkinaL.BrunetteK
