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People taking GLP-1 medications should ensure adequate daily protein intake and correct any micronutrient deficiencies, paying particular attention to iron, zinc, vitamin D, and B12. What Are the Alternatives if You Cant Take a GLP-1

Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2022

That said, a real-world analysis by Prime Therapeutics and Magellan Rx looked at integrated pharmacy and medical claims data from 16 million commercially insured members and found that a whopping 68% had stopped taking their GLP-1s after just one year

In 2025, Novo Nordisks semaglutide awaits several first-time FDA decisions: Injectable GLP-1s 2025 Ozempic for T2DM and peripheral artery disease (PAD) 2H 2025 Wegovy for heart failure with preserved ejection fraction (HFpEF) and obesity Oral GLP-1s October 2025 new indication for oral Rybelsus for secondary CV risk reduction 4Q 2025 the first oral GLP-1 ( oral formulation of Wegovy 25 mg ) for weight loss and weight loss plus secondary CV risk reduction Given the considerable continued growth expected in the GLP-1 pipeline, Prime Therapeutics (Prime) talented team of clinical experts actively monitors this emerging landscape

[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Koska J., Sands M., Burciu C., DSouza K.M., Raravikar K., Liu J., Truran S., Franco D.A., Schwartz E.A., Schwenke D.C., et al

Some studies suggest that individuals with Hashimoto's disease may develop metabolic complications beyond thyroid dysfunction itself