are glp 1 drugs safe long term As GLP-1 Use Expands, Long-Term Safety Questions Remain Under Watch long term use of glp
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Retatrutide data in diabetes populations is still emerging from the TRIUMPH trial program

doi: 10.1111/jdi.14346 51 Petkovi-DabiJBiniICariBBoiLUmievi-ipkaSBednarukNet al

The LEAN-PREP study (NCT enrolling 2025) is the first, with results expected 2026-2027

In contrast, co-treatment of semaglutide with the amylin receptor agonist cagrilintide resulted in 29% of patients with obesity and T2D reporting nausea compared to 13% for cagrilintide alone and 16% for semaglutide alone (68)
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