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It is currently in Phase 2 clinical trials for the treatment of overweight and obesity

A 2026 case report describes a 34-year-old man with obesity and alcohol use disorder whose semaglutide treatment for weight loss was associated with a marked drop in drinking over 10 months, with his AUDIT score falling from 27 to 7 and alcohol use dropping from about 15 drinks per week to half a beer per month
American Journal of Cardiology, Volume 222, 121 - 130

However, genetic variants can alter the response in some.

A Breakthrough Award, New Evidence in Parkinson's and Heart Disease
