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In the brain, the transporter, ETT, is functionally present in neurons, but not in astrocytes (58, 95)
doi: 10.3897/pharmacia.66.e37035
This dual nature has contributed to theoretical concerns
The mechanism associated with EGF receptor transactivation by glutamine is unclear
Hyperglycemia stimulates the proliferation of vascular smooth muscle cells and collagen synthesis, leading to fibrosis and hardening of the vascular wall, causing blood vessels to lose their elasticity, increasing vascular resistance and pressure, and inducing diabetic cardiovascular disease
