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bottom line: While semaglutide is generally well-tolerated, chest pain is a red flag symptom that requires immediate medical evaluation to rule out serious complications

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12 Additionally, metabolic abnormalities are strongly correlated with OA in weight-bearing and non-weight-bearing joints, suggesting that the pathogenesis of OA is linked to oxidative stress and inflammation, which are hallmarks of cardiometabolic disease

Others may develop hives, raised welts, or a Mounjaro skin reaction that spreads beyond the injection site

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Semaglutide works by mimicking a natural hormone in your body called GLP-1