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Description
Dual Agonist Unlike treatments that focus on a single hormone, tirzepatide activates both GLP-1 and GIP receptors

doi:10.1111/dom.14863

Bioorg Med

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(2005) Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression

Laufer, P
