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Rheum Dis Clin North Am 26:825839

Berthet C, Lei H, Thevenet J, Gruetter R, Magistretti PJ, Hirt L
McCord and Irwin Fridovich in 1969

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found a new biological element that can directly react with phenolic antioxidants (such as t-butylhydroquinone) in mice, and named it as antioxidant response element, also known as electrophile response element (EpRE) (Rushmore and Pickett, 1990)
