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This is because an unacceptable level of a probable carcinogen (cancer-causing agent) was found in some extended-release metformin tablets

These next-generation agents may address some current limitations while potentially introducing new challenges

'My whole life I had a thick and luxurious head of hair

4 The burden of MASLD is projected to increase exponentially, with anticipated rises of 21% and 63% in cases of MASLD and MASH, respectively

This is the data behind the muscle-and-nutrient concern, drawn from the largest claims analysis to date , Butsch and colleagues' retrospective study of 461,382 US adults newly prescribed GLP-1RAs (Butsch et al., Obesity Pillars, 2025

they found no significant difference between GLP-1 RA combination therapy vs